Synthesis and antiviral activity of several quinoline derivatives

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Abstract

The antiviral activity of 2-substituted and 2,6-disubstituted quinoline-4-carboxylic acids and their derivatives has been studied against orthopoxviruses on Vero and MK-2 cell cultures. High activity has been found for 2-(1,1′-biphenyl-4-yl)quinoline-4-carboxylic acid. © 2011 Springer Science+Business Media, Inc.

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Zemtsova, M. N., Zimichev, A. V., Trakhtenberg, P. L., Klimochkin, Y. N., Leonova, M. V., Balakhnin, S. M., … Belanov, E. F. (2011). Synthesis and antiviral activity of several quinoline derivatives. Pharmaceutical Chemistry Journal, 45(5), 267–269. https://doi.org/10.1007/s11094-011-0613-z

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