Cirugía cardiaca con circulación extracorpórea: Síndrome vasoplégico y vasopresina

Abstract

Cardiac surgery with cardiopulmonary bypass is associated with systemic infl am matory response. In some cases this clinical condition is characterized by severe hypotension due to low systemic vascular resistance during and after cardiopulmonary bypass. A few of these cases do not respond to volume or catecholamines. This condition is known as vasoplegic syndrome. Its etiology is not fully understood today and carries associated morbidity and mortality. In this syndrome, vasopressin levels are reduced, as in septic and hypovolemic shock. Supplementary vasopressin improves blood pressure and might be considered as an alternative treatment. Several reports have shown benefi ts when used alone or in combination with catecholamines. However, further studies are necessary to fi nd the most appropriate use of the drug for vasoplegic syndrome.