A new phenanthrene glycoside and other constituents from Dioscorea opposita

Abstract

Phytochemical investigation of the rhizome of Dioscorea opposita has led to the isolation of a new phenanthrene glycoside, 3,4,6-trihydroxyphenanthrene-3- O-β-D-glucopyranoside (1), and five known compounds, soyacerebroside I (2), adenosine (3), β-sitosterol (4), palmitic acid (5) and palmitoyloleoylphosphatidylcholine (6). Their structures were determined by spectroscopic methods, including 1D- and 2D-NMR. Compounds 1-6 exhibited no antifungal activity against the human pathogenic yeasts Candida albicans, C. glabrata and C. tropicalis. © 2004 Pharmaceutical Society of Japan.