Exposure to dibutyl phthalate induced the growth inhibition and oxidative injury in Dunaliella salina

Abstract

Dibutyl phthalate (DBP) is a persistent organic pollutant that poses a threat to aquatic ecosystems. In order to study the ecological toxicological mechanism of DBP on marine microalgae. Dunaliella salina was chosen as the experimental material. We investigated the cell growth, hydrogen peroxide (H2O2) content, malondialdehyde (MDA) content, superoxide dismutase (SOD) and glutathione peroxidase (GPx) activities of D. salina exposed to different DBP concentrations. Exposure to low concentrations of 0.1 mg/L DBP promoted the cell growth of D. salina. As the concentrations of DBP increased, the growth of D. salina was gradually inhibited. The GPx and SOD activities of D. salina reduced significantly exposed to DBP concentrations of 50 and 100 mg/L. When D. salina was exposed to 100 mg/L DBP, the MDA and H2O2 contents of D. salina increased with time from the second day. The results provided theoretical support for studying the toxicity mechanism of DBP.