Strategies for Drawing Quantitative Conclusions from Nontargeted Liquid Chromatography-High-Resolution Mass Spectrometry Analysis

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Abstract

This Feature aims at giving an overview of different possibilities for quantitatively comparing the results obtained from LC-HRMS-based nontargeted analysis. More specifically, quantification via structurally similar internal standards, different isotope labeling strategies, radiolabeling, and predicted ionization efficiencies are reviewed.

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Kruve, A. (2020, April 7). Strategies for Drawing Quantitative Conclusions from Nontargeted Liquid Chromatography-High-Resolution Mass Spectrometry Analysis. Analytical Chemistry. American Chemical Society. https://doi.org/10.1021/acs.analchem.9b03481

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