The Effect of temperature on Bisphenol: An elution from dental resins

Abstract

Aim: Bisphenol A (BPA) elution from baby bottles into contenthas been of great public interest and debate in recent year.Uncontrolled BPA elution due to temperature increase maycreate a risk factor for human health. However, dental resins thatare used in pediatric dentistry also have BPA derivatives. Theaim of this study is to evaluate BPA elution from dental resins andto determine the effect of temperature increase on this elution.Materials and methods: Four dental resins containing BPAderivatives (Filtek Z250, Filtek Supreme XT, Fissurit FX, andAdmira) and a control group (BPA free G-aenial) were used inthis study. Each specimen was stored in 2 ml of 75% ethanolwatersolution at 37°C. Water at a temperature of 59°C ± 1°C(preferred temperature of hot drinks) was added to the studysamples at certain time intervals (1, 6, 24 hours and 2, 3, 4,5 and 6 days). The methanol samples were analyzed usinghigh-performance liquid chromatography (HPLC). Data wasanalyzed using multivariate and repeated measures analysisof variance (p < 0.05).Results: The study samples generally eluted more BPA thanthe control samples (p < 0.05). The greatest amount of BPA foran individual time period was measured after 6 hours for thegroups A to D; the same was found after 24 hours for group E.Conclusion: While the BPA elution levels evaluated in thestudy samples were more than control samples, all measuredvalues were under the reference levels and the amounts donot constitute a risk. Clinical significance: Resin-based dental materials can act asa source of BPA (within safety margins), especially when theyreact with hot water.