Bagremycin A and B, novel antibiotics from Streptomyces sp. Tü 4128

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Abstract

Two novel secondary metabolites, bagremycin A (2) and B (3), were detected in the culture filtrate of Streptomyces sp. Tü 4128 by HPLC-diode-array screening. They are phenol esters of 3-amino-4-hydroxybenzoic acid with a derivative of p-coumaric acid and show a moderate activity against Gram-positive bacteria and some fungi.

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Bertasso, M., Holzenkämpfer, M., Zeeck, A., Dall’Antonia, F., & Fiedler, H. P. (2001). Bagremycin A and B, novel antibiotics from Streptomyces sp. Tü 4128. Journal of Antibiotics, 54(9), 730–736. https://doi.org/10.7164/antibiotics.54.730

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