Efficient technique for quantification of chlorantraniliprole residue in/on vegetables and soil using GC-MS/MS

Abstract

An analytical method for the determination of chlorantraniliprole residue in brinjal, capsicum, chilli, cucumber, tomato and soil samples using GC-MS/MS was developed and validated to fulfil the requirements of the SANTE/11813/2017 to support compliance with ISO/IEC 17025. The objective of the validation was to evaluate all required parameters, such as linearity of analytical curves, instrument and method limits of detection and quantification, matrix effects, accuracy (trueness and precision) using modified QuEChERS method. The overall recoveries of the method ranged between 84-98% for the vegetable and soil samples, spiked at 0. 005, 0. 01, 0. 05, 0. 1 and 0. 2 µg / ml. GC-MS/MS parameters were tuned up to optimize limits of quantification (0. 005 µg /mL for vegetables and 0. 01 µg /mL for soil). Repeatability and reproducibility of method was excellent (RSD>10%) for all evaluated matrices. Hence, a fast and efficient gas chromatography-tandem mass spectrometry method with acceptable performance was achieved for routine monitoring and surveillance programme for chlorantraniliprole in soil and vegetable matrices.