The effect of tea polyphenol (TP) on cognitive and anti-cholinesterase activity was examined in scopolamine-treated mice. Chronic administration of TP significantly reversed scopolamine-induced retention deficits in both step-through passive avoidance and spontaneous alternation behavior tasks. Furthermore, TP exhibited a dramatic inhibitory effect on acetylcholinesterase activity. This finding suggests that TP might be useful in the treatment of Alzheimer's disease.
CITATION STYLE
Kim, H. K., Kim, M., Kim, S., Kim, M., & Chung, J. H. (2004). Effects of green tea polyphenol on cognitive and acetylcholinesterase activities. Bioscience, Biotechnology and Biochemistry, 68(9), 1977–1979. https://doi.org/10.1271/bbb.68.1977
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