Stachybotrins A and B: Novel Bioactive Metabolites from a Brackish Water Isolate of the Fungus Stachybotrys sp.

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Abstract

Stachybotrins A and B (1 and 2), two new aromatic alkaloids with antibacterial and antifungal activity, have been isolated from an aquatic isolate of a new species of the genus Stachybotrys (CS-710-1). Compounds 1 and 2 were obtained from ethyl acetate extracts of liquid cultures by preparative TLC. The structures were determined primarily by analysis of HMBC, HMQC, COSY, and NOESY experiments. © 1992, American Chemical Society. All rights reserved.

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Xu, X., de Guzman, F. S., Gloer, J. B., & Shearer, C. A. (1992). Stachybotrins A and B: Novel Bioactive Metabolites from a Brackish Water Isolate of the Fungus Stachybotrys sp. Journal of Organic Chemistry, 57(25), 6700–6703. https://doi.org/10.1021/jo00051a006

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