Differential pulse voltammetry technique for the determination of imipramine, dopamine and norepinephrine using a hydroquinone derivative multi-wall carbon nano-tube carbon paste electrode

Abstract

In this study, a synthetic para dihydroxy benzene derivative was used for electro-catalytic determination of chemical and biological species. The modified electrode was fabricated using graphite powder, multi-wall carbon nano tubes and the synthetic compound. The analytes including imipramine, dopamine and norepinephrine were quantitied. The kinetic parameters were calculated. Based on the obtained results, the modified electrode shifted the electro-catalytic oxidation potential about 490 mV for imipramine. Analytical parameters including the limit of detection and linear dynamic range were determined using differential pulse voltammetry technique. Simultaneous determination of imipramine, norepinephrine and dopamine along with the individual determination of imipramin were studied. The method applied in urine sample with satisfactory results.