Ashitaba ( Angelica keiskei) Exerts Possible Beneficial Effects on Metabolic Syndrome

Abstract

Metabolic syndrome is a serious health condition comprising a combination of glucose metabolism disorder, high blood pressure and obesity. The main underlying risk factors for metabolic syndrome are abdominal obesity and insulin resistance. Various studies have shown that herbal medicines can effectively reduce the risk of developing metabolic syndrome. Angelica keiskei Koidzumi (ashitaba), a large perennial herb native to the Southeast Pacific coast of Japan, has recently become a popular herbal medicine, dietary supplement and health food in Asian countries. Ashitaba leaves, stems and roots contain abundant nutrients and dietary fiber, as well as various natural substances such as chalcones, flavanones and coumarins. Various physiological and biological activities of ashitaba and its natural derivatives have recently been demonstrated in numerous studies. The accumulated evidence emphasizes ashitaba health benefits and supports its most common use against metabolic syndrome. Here, we summarize current information derived from studies on the effects of ashitaba on various pathological disorders associated with metabolic syndrome.