Noonan syndrome with loose anagen hair associated with trichorrhexis nodosa and trichoptilosis

Abstract

We report a case of Noonan syndrome with loose anagen hair ( NS / LAH ), a rare variant of Noonan syndrome, with associated trichorrhexis nodosa and trichoptilosis. The SHOC 2 mutation may be responsible for these additional hair shaft defects, revealing the importance of microscopic examination of hairs in these patients.