Molecular characterization of an Australian serotype 1 Streptococcus pneumoniae outbreak

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Abstract

Serotype 1 Streptococcus pneumoniae is a cause of invasive pneumococcal disease (IPD) worldwide and has been associated with IPD outbreaks, while carriage is rarely detected in healthy adults or children. This study details an Australian multi-state and territory outbreak of serotype 1 S. pneumoniae IPD between 2010 and 2012. Molecular characterization demonstrated the outbreak was largely due to the clonal expansion of sequence type 306, MLVA type 261 S. pneumoniae serotype 1.

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Staples, M., Graham, R. M. A., Jennison, A. V., Ariotti, L., Hicks, V., Cook, H., … Smith, H. V. (2015). Molecular characterization of an Australian serotype 1 Streptococcus pneumoniae outbreak. Epidemiology and Infection, 143(2), 325–333. https://doi.org/10.1017/S0950268814000648

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