A case report: rapid progression of coronary atherosclerosis in a patient taking Targretin (Bexarotene)

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Abstract

Anti-neoplastic drugs have made major advancements in oncology, however they are not without cardiovascular consequences. We present a patient with cutaneous T-cell lymphoma receiving Targretin therapy who presented with accelerated atherosclerosis. His triglyceride level (TG) was greater than 1000 mg/dL, which rapidly improved with discontinuation of Targretin.

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DeAngelo, S., Mann, K. I., Abdulbasit, M., Ahnert, A., & Sundlöf, D. W. (2020). A case report: rapid progression of coronary atherosclerosis in a patient taking Targretin (Bexarotene). Cardio-Oncology, 6(1). https://doi.org/10.1186/s40959-020-00087-3

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