Hyperbilirubinemia in the newborn

Abstract

• Based on strong research evidence, breastfeeding, prematurity, significant jaundice in a previous sibling, and jaundice noted before discharge from the nursery are the most common risk factors associated with severe hyperbilirubinemia. (13) • Based on research evaluating benefit versus harm, jaundice in the first 24 hours after birth is not physiologic jaundice and needs further evaluation. • All newborns should undergo a risk assessment for hyperbilirubinemia before discharge from the newborn nursery and have appropriate follow-up evaluation after discharge. • Visual assessment of jaundice does not assess the TSB reliably; clinicians should check either a TSB or TcB when in doubt. • The infant's age in hours is used when evaluating and managing bilirubin concentrations.