Multi-residue analysis of 18 organochlorine pesticides in 10 traditional Chinese medicines by Gas Chromatography (GC)

Abstract

A rapid and simple method for the simultaneous analysis of 18 pesticides (α-(C 6H 6Cl 6)-Benzene hexachloride, β-BHC, γ-BHC, δ-BHC, heptachlor, heptachlor epoxide, tecnazene, pentachloronitrobenzene (PCNB), hexachlorobenzene, aldrin, methyl pentachlorophenyl sulphide (MPCPS), α-endosulfan, trans-chlorodane, cis-chlorodane, p,p′-(C 14H 8Cl 4)- Dichlorodiphenyl dichloroethylene, o,p′-(C 14H 9Cl 5)-Dichlorodiphenyl trichloroethane, p,p′-(C 14H 10Cl 4)-Dichlorodiphenyl dichloeoethane, p,p′-DDT) by gas chromatography (GC) in 10 Traditional Chinese Medicines (TCMs) has been developed. The limit of detection was found to be 1.2 × 10 -13 to 9.0 × 10 -13 g with the recoveries ranging from 72.9 to 114.5% and Relative Standard Deviation being less than 17.5%. In addition, the assay was applied to monitor the residues in 10 TCMs, amongst which at least one of the above pesticides were found in 67 samples. The results showed that α-BHC was the most frequently detected with a presence of 44.6% in the tested samples, whilst heptachlor epoxide, trans-chlorodane, cis-chlorodane and p,p′-DDD were not detected at all. Nonetheless, none of pesticides in all samples appeared to exceed themaximum residue limits (MRLs) seen in the Chinese regulations.