Abstract
Background: Fragile X syndrome (FXS) is the most common inherited cause of intellectual disability. The aim of our longitudinal study was to describe ageing-related cognitive changes in men with FXS. Method: A neuropsychologist determined the raw scores (RSs) of 19 men with FXS twice with the Leiter International Performance Scale at an average interval of 22 years. The ages of the participants at baseline ranged from 16 to 50 (mean 27) years. Results: At follow-up, the RSs improved in two men, remained the same in two men and declined in 15 men. Overall, the RS of the study group deteriorated by an average 4 points in RSs (p
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Sauna-aho, O., Bjelogrlic-Laakso, N., Rautava, P., & Arvio, M. (2020). Ageing and cognition in men with fragile X syndrome. Journal of Applied Research in Intellectual Disabilities, 33(5), 1113–1118. https://doi.org/10.1111/jar.12733
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