Abstract
A new prenylated naphthoquinone antibiotic, fumaquinone (5,7-dihydroxy-2-methoxy-3-methyl-6-(3-methyl-but-2-enyl)[1,4]naphthoquinone) was isolated from cultures of Streptomyces fumanus (LL-F42248). Its chemical structure was determined primarily by NMR spectroscopy. Preliminary feeding experiments indicated the naphthoquinone is of polyketide origin, while the O-methyl and aromatic C-methyl groups are derived from methionine. © Japan Antibiotics Research Association.
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Charan, R. D., Schlingmann, G., Bernan, V. S., Feng, X., & Carter, G. T. (2005). Fumaquinone, a new prenylated naphthoquinone from streptomyces Fumanus. Journal of Antibiotics, 58(4), 271–274. https://doi.org/10.1038/ja.2005.32
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