B-cell lymphoma: Suppressing a tumor suppressor

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Abstract

The BCL-6 oncogene can downregulate expression of the p53 tumor suppressor gene in B cell lymphoma. This pathway probably exists to protect normal germinal-center B cells from apoptosis induced by DNA mutations.

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APA

Dent, A. (2005, January). B-cell lymphoma: Suppressing a tumor suppressor. Nature Medicine. https://doi.org/10.1038/nm0105-22

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