Development on Application of Phenazine Derivatives in Molecular Recognition and Self-assembly

Abstract

A wide variety of phenazine compounds are no stranger to organic chemistry researchers, it widely exists in organic natural products together with good biological activity. The synthetic process is simple and the functionalization of molecular structure is comparatively easy of phenazine compounds with natural skeleton. These compounds with multiple sites and large conjugated system, which make it easy to form hydrogen bond, ionic bond and π-π interaction and so on. Therefore, the phenazine compounds have extensive application in supramolecular chemistry. Molecular recognition (MR) and supramolecular self-assembly (MS-A) are two important research direction of supramolecular chemistry. The advances in the research of the development on application of phenazine derivatives in MR and MS-A in recent years are highlighted. According to different type of guest, the MR is grouped into three categories, including anion recognition (AR), cationic recognition (CR) and neutral molecular recognition (NMR). According to the difference of induction factors between guest and phenazine derivatives, the MS-A is grouped into four categories, including self-assembly induced by hydrogen bonding (HBSA), self-assembly induced by accumulation (ASA), self-assembly induced by metal-ligand (M-LSA), self-assembly induced by cooperation of multiple factors (MFSA), and self-assembly induced by the outside environment (OESA).