Microwave-assisted synthesis and antifungal activity of some novel thioethers containing 1,2,4-triazole moiety

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Abstract

A series of novel thioether derivatives containing 1,2,4-triazole moiety were designed and synthesized from 4-chlorophenol and ethyl 2-chloroacetate as starting materials by multi-step reactions under microwave irradiation, and their structures were characterized by 1H-NMR, MS and elemental analysis. The antifungal activity of title compounds was determined. The results indicated that some of title compounds exhibited moderate antifungal activity.

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Min, L. J., Shi, Y. X., Wu, H. K., Sun, Z. H., Liu, X. H., Li, B. J., & Zhang, Y. G. (2015). Microwave-assisted synthesis and antifungal activity of some novel thioethers containing 1,2,4-triazole moiety. Applied Sciences (Switzerland). MDPI AG. https://doi.org/10.3390/app5041211

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