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MYC-a thorn in the side of cancer immunity

Cell Research
DOI: 10.1038/cr.2016.50
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Abstract

For decades, MYC has been known for its role in regulating cancer cell proliferation and survival. In a recent paper published in Science, Casey et al. have uncovered a new function for MYC in promoting immune evasion by directly regulating expression of programmed death-ligand 1 (PD-L1) and CD47 on cancer cells.

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Spranger, S., Gajewski, T. F., & Kline, J. (2016, June 1). MYC-a thorn in the side of cancer immunity. Cell Research. Nature Publishing Group. https://doi.org/10.1038/cr.2016.50

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