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Palladium-Catalyzed Ortho-Arylation of Carbamate-Protected Estrogens

Journal of Organic Chemistry (2016) 81(9) 3473-3478
DOI: 10.1021/acs.joc.6b00532
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Abstract

The palladium-catalyzed ortho-arylation of diethyl carbamate-protected estrone and estriol with aryl iodides gives the 2-arylated analogues. Subsequent removal of the carbamate directing group furnishes 2-arylated estrone, estradiol, or estriol depending on the method used.

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APA

Bedford, R. B., Brenner, P. B., Durrant, S. J., Gallagher, T., Méndez-Gálvez, C., & Montgomery, M. (2016). Palladium-Catalyzed Ortho-Arylation of Carbamate-Protected Estrogens. Journal of Organic Chemistry, 81(9), 3473–3478. https://doi.org/10.1021/acs.joc.6b00532

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