Cancer therapy system based on gold nanoparticle / cold plasma via stimulated singlet oxygen production

Abstract

Gold nanoparticles have unique physical/chemical properties which let them very useful in several applications. In addition, to their biocompatibility which is very important for biomedical applications. Recently gold nanoparticles and reactive species of cold plasma have been successfully used for tumor cells and cancer treatment. This method depends on the type of reactive ionized species or the size of gold nanoparticles which it produces and its directed effect on the cell cycle. Our proposed novel designed system which combines both gold nanoparticles and reactive species of nitrogen and argon cold plasma is obtained. Therefore, generating singlet oxygen and reactive species with confirming gold nanoparticles stability as well as to its exposure to cold plasma at different conditions and time periods is accomplished. The analysis of this system will be done using Raman spectroscopy technique. This procedure will enhance better, direct, effective and selective targeting for different kinds of bio-threats such as tumor cells, bacteria, fungi, and virus. This innovative system may be used as a new sterilized technique for different fields such as medical and biological sector, and more promise as cancer therapy selective technique.