Dendrimer Applications for Cancer Therapies

Abstract

Human cancer therapy is a major issue in modern medical science. Lots of emerging materials are developing rapidly. Dendrimers, as a nanocarrier, are now widely used in the field of biomedicine, pharmacy, and so on. As a super-branched macromolecule, dendrimers have a series of outstanding properties. Such as simple to functionalize, have nano & symmetric dimension and cavities for host-guest entrapment. It has made much progress in drug and gene delivery. Dendrimers have higher efficiency by perfecting the surface modification methods. The small molecules, DNAs, therapeutic agents, and more can be loaded into dendrimers. Also, the cytotoxicity is reducing gradually. This review aims to make a summary of dendrimers' history and provide guidance for future research. This review gives a brief review of dendrimers' properties, presents how dendrimers developed in drug and gene delivery, what drawbacks are remaining to resolve.