Microwave-assisted efficient synthesis of dihydro pyrimidines: Improved high yielding protocol for the Biginelli reaction

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Abstract

DihydropyrJmidJnes were synthesJsed in high yields by one-pot cyclocondensation reaction of aldehydes, aceto-acetates and urea using various acid catalysts like Amberlyst-15, Nafion-H, KSF clay and dry acetic acid under microwave irradiation.

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Yadav, J. S., Subba Reddy, B. V., Jagan Reddy, E., & Ramalingam, T. (2000). Microwave-assisted efficient synthesis of dihydro pyrimidines: Improved high yielding protocol for the Biginelli reaction. Journal of Chemical Research - Part S, (7), 354–355. https://doi.org/10.3184/030823400103167633

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