Embryo coculture: A review

Abstract

Since the inception of in-vitro fertilization, various attempts have been made to improve in-vitro embryo development, therebyenhancing implantation and in turn, pregnancy rates. Coculture, the simultaneous culture of somatic cells together with theembryo, is one strategy that has been used to achieve this goal. We review the rationale behind the technique of coculture, currentmethods utilized, and the evidence supporting its use.