Comparison of intravenous medetomidine and medetomidine/ketamine for immobilization of free-ranging variable flying foxes (pteropus hypomelanus)

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Abstract

Medetomidine (0.03 mg/kg) and medetomidine/ketamine (0.05/5.0 and 0.025/2.5 mg/kg), administered by intravenous injection, were evaluated for short-term immobilization of wild-caught variable flying foxes (Pteropus hypomelanus). Medetomidine alone produced incomplete chemical restraint and a stressful, prolonged induction. Both ketamine/medetomidine doses produced a smooth induction and complete immobilization. The combined medetomidine/ketamine dose of 0.025/2.5 mg/kg produced a rapid induction (232±224 sec) with minimal struggling and vocalization, a complete and effective immobilization period, and tended to lead to a faster and better quality recovery than medetomidine alone or a higher dose of medetomidine and ketamine (0.05/5.0 mg/kg), thus reducing holding time and permitting an earlier release of the bat back into the wild. © 2011 Epstein et al.

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Epstein, J. H., Zambriski, J. A., Rostal, M. K., Heard, D. J., & Daszak, P. (2011). Comparison of intravenous medetomidine and medetomidine/ketamine for immobilization of free-ranging variable flying foxes (pteropus hypomelanus). PLoS ONE, 6(10). https://doi.org/10.1371/journal.pone.0025361

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