Saponins and other constituents from the leaves of Aralia elata

Abstract

A new triterpenoid saponin, together with five known saponins, were isolated from the nonpolar n-hexane fraction of the leaves of Aralia elata. The structure of the new saponin, durupcoside C, was elucidated as hederagenin 3-O-β-D-glucopyranosyl(1→3)-β-D-glucopyranosyl(1→3) -α-L-arabinopyranoside on the basis of spectroscopic analysis. The known saponins were characterized as 3-O-α-L-rhamnopyranosyl(1→2)-α- L-arabinopyranosyl hederagenin 28-O-β-D-xylopyranosyl(1→6)-β-D- glucopyranosyl ester, hederagenin 3-O-β-D-glucopyranosyl(1→3)-α- L-rhamnopyranosyl(1→2)-α-L-arabinopyranoside, oleanolic acid 3-O-β-D-glucopyranosyl(1→3)-α-L-rhamnopyranosyl(1→2) -α-L-arabinopyranoside, hederagenin 3-O-α-L- rhamnopyranosyl(1→2)-α-L-arabinopyranoside (α-hederin), and hederagenin 3-O-β-D-glucopyranosyl(1→3)-α-L-arabinopyranoside (collinsonidin). In addition, two known lipids, Arisaema glyceride 3 and ceramide mixtures were also isolated and characterized. Collinsonidin and two known lipids were isolated for the first time from this plant. © 2005 Pharmaceutical Society of Japan.