Orthostatic Intolerance in Children With Long COVID Utilizing a 10-Minute Passive Standing Test

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Abstract

Despite there being a wide variety of symptoms reported in pediatric long COVID, one condition that has become increasingly recognized is orthostatic intolerance (OI), which can cause significant morbidity, limiting activities of daily living. This study examines rates of OI in 92 children with long COVID who underwent a bedside passive standing test in a pediatric post-COVID-19 rehabilitation clinic. Seventy-one percent met criteria for an orthostatic condition, including postural orthostatic tachycardia syndrome (POTS), orthostatic tachycardia (OT), classic orthostatic hypotension (OH), delayed OH, and orthostatic hypertension. Our findings suggest that OI is common in pediatric long COVID, necessitating appropriate clinical screening and treatment.

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Morrow, A. K., Villatoro, C., Kokorelis, C., Rowe, P. C., & Malone, L. A. (2025). Orthostatic Intolerance in Children With Long COVID Utilizing a 10-Minute Passive Standing Test. Clinical Pediatrics, 64(3), 416–424. https://doi.org/10.1177/00099228241272053

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