Abstract
Nucleosome-protein complexes stick to the air-water interface and denature upon plunge freezing for cryoEM. Here, authors Chio and Palovcak et al. develop EM grids that protect such complexes and use these grids to study the ATP-dependent chromatin remodeler SNF2h.
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CITATION STYLE
APA
Chio, U. S., Palovcak, E., Smith, A. A. A., Autzen, H., Muñoz, E. N., Yu, Z., … Cheng, Y. (2024). Functionalized graphene-oxide grids enable high-resolution cryo-EM structures of the SNF2h-nucleosome complex without crosslinking. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-46178-y
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