Synthesis of beta-proline like derivatives and their evaluation as sodium channel blockers

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Abstract

(Chemical Equation Presented) A simple and convenient procedure for the preparation of beta-proline like derivatives in their racemic and optically active forms has been reported. The compounds have been screened for their potential activity as sodium channel blockers.

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Muraglia, M., Franchini, C., Corbo, F., Scilimati, A., Sinicropi, M. S., De Luca, A., … Tortorella, V. (2007). Synthesis of beta-proline like derivatives and their evaluation as sodium channel blockers. Journal of Heterocyclic Chemistry, 44(5), 1099–1103. https://doi.org/10.1002/jhet.5570440519

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