Aβ Puts the Alpha in Synuclein

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Abstract

Neurodegenerative diseases like Alzheimer's disease and Parkinson's disease are characterized pathologically by aberrant protein accumulation, such as Aβ or α-synuclein deposition. In this issue of Neuron, Bassil et al. (2020) observed an exacerbation of α-syn pathology in the presence of Aβ plaques in vivo, with comorbid pathologies associated with greater neurodegeneration.

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Cook, C., & Petrucelli, L. (2020, January 22). Aβ Puts the Alpha in Synuclein. Neuron. Cell Press. https://doi.org/10.1016/j.neuron.2020.01.001

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