Isolation, Structural Elucidation, and Bioactivity Studies of Leaf Extract of Vernonia Amygdalina

Abstract

Vernonia Amygdalina (VA) is a tropical African plant of the Asteraceae family and is occasionally cultivated for its medicinal uses, which include as a treatment for diarrhea, skin wounds, fever mastitis and worms infection. The aim of this study is to isolate and elucidate the structure of some of the chemical constituents from the leaf of Vernonia Amygdalina and its bioactivities. The methanol extract of Vernonia Amygdalina, after repeated chromatography led to the isolation of a different compound, one of this compound (MM-4) is partially characterized based on the spectral data (IR, 1 H NMR, 13 C NMR, and DEPT) and extracts from Vernonia Amygdalina has been shown to have antimicrobial activity.