Caffeine mediated changes of sex ratio in chinese hamsters, Cricetulus griseus

Abstract

Sixty 6 to 10 wk old male Chinese hamsters were assigned to 2 groups. In one, the animals were untreated and in the other, they were treated with 0.02 g caffeine/100 ml water orally for 60 days. The sex ratio of the resulting litters showed a significant (P<0.025) skewing towards females (61.4%) when compared to that of the controls (49.2%).