PINK1: From Parkinson's disease to mitophagy and back again

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Abstract

The genetics of Parkinson's disease has been key to unravelling the PINK1-dependent mitophagy process. Here, we discuss the implications of a 2010 PLOS Biology paper that shed light on the functional importance of PINK1 in the mitophagy cascade.

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O’Callaghan, B., Hardy, J., & Plun-Favreau, H. (2023). PINK1: From Parkinson’s disease to mitophagy and back again. PLoS Biology, 21(6 June). https://doi.org/10.1371/journal.pbio.3002196

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