High performance capillary electrophoresis

Abstract

Currently, capillary electrophoresis is being developed as an instrumental approach to electrophoresis. The author discusses two approaches in capillary electrophoresis. First, in open capillary operation, we have incorporated chemical selectivity along with high performance separation for resolution of closely related species. The second approach involved the use of polyacrylamide gel capillary columns to provide a medium analogous to slab gel operation. We have successfully produced stable columns for the separation of important mixtures.