Adverse Effects of Using 0.12% Chlorhexidine Digluconate: A Literature Review

Abstract

As a chemical control, 0.12% chlorhexidine digluconate is the most widespread in the lineage of mouthwashes. In addition to the effective action of chlorhexidine in dental biofilm, its use is also indicated for oral mucositis, as it acts in reducing the severity of injuries, providing more comfort and avoiding secondary infections. However, the use of chlorhexidine for prolonged periods is contraindicated, as it induces side effects such as discoloration of the teeth, peeling of the mucosa, altered taste and unpleasant taste. In our literature review work, we concluded that 0.12% chlorhexidine digluconate is an excellent antimicrobial agent, but its use should be done with discretion, as it has significant adverse effects. Introduction