Abstract
Substitution of 4-methyl-[1,8]-naphthyridine in 2 and 7 position by alkylamines leads to highly fluorescent compounds. The arrangement of hydrogen donor and acceptor groups of these naphthyridines allows interactions with guanine and guanine cytosine base pairs. The described synthesis offers easy access to these small and stable fluorescent probes.
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Hoock, C., Reichert, J., & Schmidtke, M. (1999). Fluorescent 2,7-dialkylamino-[1,8]-naphthyridines: Preparation and spectroscopic properties. Molecules, 4(10), 264–271. https://doi.org/10.3390/41000264
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