Abstract
Three new highly oxygenated pimarane diterpenoids, sarcosenones A-C (1-3), and the known 9α-hydroxy-1,8(14),15-isopimaratrien-3,7,11-trione (4), were isolated from cultures of an endolichenic fungus Sarcosomataceae sp. Their structures were elucidated based on NMR spectroscopic data and electronic circular dichroism (ECD) calculations. Compound 1 showed moderate cytotoxicity against a small panel of four human tumor cell lines, with IC50 values of 7.5-26.4 μM.
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CITATION STYLE
Hou, X., Xu, Y., Zhu, S., Zhang, Y., Guo, L., Qiu, F., & Che, Y. (2020). Sarcosenones A-C, highly oxygenated pimarane diterpenoids from an endolichenic fungus: Sarcosomataceae sp. RSC Advances, 10(26), 15622–15628. https://doi.org/10.1039/d0ra02485f
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