Fatores prognósticos da infeção respiratória aguda baixa grave em crianças menores de 5 anos na Colômbia

Abstract

Introduction: Acute lower respiratory infection (alri: community acquired and/or bronchiolitis) is one of the main public health issues for children under five years of age. The main purpose of this research was to describe the epidemiological profile, associated factors, and prognosis of alri in two hospitals in Popayan, Colombia. Materials and Methods: This was a cohort study. We included children from 2 months to 5 years of age with diagnoses of severe alri. Sociodemographic profiles, clinical features, and prognostic factors were collected. The main outcomes under study were mortality, admission to icu, and length of stay. Multivariable analyses were performed to establish the independent contributions of prognostic factors. Results: 121 patients were included. Incidence of alri was 4% ci95% [3,3-4,7] during 6 months of follow-up. Mortality during follow-up was 0,8% (ci95% 0,l-4,4) (one patient). Thirty three percent of children required admission to icu. Median length of stay was 5 days and length of stay in icu was 4 days. Preterm birth was independently associated with icu admission (or=5,1 ci95% [l,3-20] p=0,0l9). Discussion: The incidence of severe alri was 4%. Mortality was low and length of stay was short. Factors related to the diagnosis of alri in this cohort are consistent with those reported in the national and international literature, and the only independent prognostic factor for admission to icu was preterm birth.