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Genetic immunization with adeno-associated virus vectors expressing herpes simplex virus type 2 glycoproteins B and D

  • Manning W
  • Paliard X
  • Zhou S
  • et al.
Journal of Virology (1997) 71(10) 7960-7962
DOI: 10.1128/jvi.71.10.7960-7962.1997
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Abstract

Intramuscular injection of mice with an adeno-associated virus (AAV) vector expressing herpes simplex virus type 2 glycoprotein B led to the generation of both gB-specific major histocompatibility complex class I-restricted cytotoxic T lymphocytes and anti-gB antibody. AAV-mediated immunization was more potent than plasmid DNA or protein in generating antibody responses.

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APA

Manning, W. C., Paliard, X., Zhou, S., Pat Bland, M., Lee, A. Y., Hong, K., … Dwarki, V. (1997). Genetic immunization with adeno-associated virus vectors expressing herpes simplex virus type 2 glycoproteins B and D. Journal of Virology, 71(10), 7960–7962. https://doi.org/10.1128/jvi.71.10.7960-7962.1997

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