Identification of new compounds from Fumaria parviflora Lam

Abstract

Fumaria parviflora Lam. (Fumariaceae) is a traditional medicinal herb chiefly used as a blood, skin and liver related disorder along with several human ailments like abdominal cramps, diarrhea, fever, antidyspeptic, cholagogue, diaphoretic, diuretic, laxative, sedative, tonic and syphilis. Phytochemical investigation of a methanolic extract of the plant of the plant led isolation of six new compounds characterized as 2-hexadecanoxybenzyl alcohol (2), 2-O-β-D-arabinopyranosyloxy-2'-O-β-D-arabinopyranosyl-(8'''-geranilanyl) benzoate (3), n-tetracosanoyl- O-β-D-arabinopyranoside (4), n-tetracosanoyl O-β-D-arabinopyranosyl-(2'→1")-O-β-D- arabinopyranoside (5), 2,6,7- trihydroxynaphthyl-2-O-β-D-glucopyranosyl-(6a→1b)-O-β-D-glucopyranosyl-(6b→1c)-O-β-D-glucuranopyranosyl-(2c→1d)-O-β-D-glucuranopyranosyl-2d-n-octadecanoate (6) and 2-hydroxy benzoic acid-2-O-β-D-arabinopyranosyl-(2a→1b)-O-β-D-arabinopyranosyl-(2b→1c)-O-β-D-arabinopyranosyl-(2c→1d)-O-β-D-glucuranopyranosyl-2d-(2',6',10',14'-tetramethyl)-n-hexadecan-1'-oate (7) along with a known fatty acid n- triacontanoic acid (1). The structural elucidations of the compounds were established on the basis of spectral data analysis and chemical means.