Multiple, pigmented, verrucous, cutaneous lesions in a 2-year-old female cat were pathologically examined. The lesions were linearly arranged on the right side of the body, and had developed along with moderate pruritus since infancy. Histologically, prominent exophytic, papillomatous outgrowths of the epidermis and acanthosis with intense ortho and parakeratotic hyperkeratosis were characteristic of the lesions. Dermal inflammation with mononuclear cells, neutrophils, and eosinophils was also noted. Inclusion bodies, cellular degeneration, and intranuclear viral particles suggesting papillomavirus infection in the keratinocytes were not observed. Papillomavirus antigen and DNA were not detected in the lesions by immunohistochemistry and polymerase chain reaction, respectively. In accordance with these clinical and histopathological features, the cutaneous lesions of the present cat were diagnosed as epidermal nevi, which were consistent with human inflammatory linear verrucous epidermal nevi. © 2012 The Japanese Society of Veterinary Science.
CITATION STYLE
Sato, M., Kariya, K., Matsumoto, M., Itoh, M., Kobayashi, Y., Nishifuji, K., … Shirota, K. (2012). Feline epidermal nevi resembling human inflammatory linear verrucous epidermal nevus. Journal of Veterinary Medical Science. https://doi.org/10.1292/jvms.12-0117
Mendeley helps you to discover research relevant for your work.