Rapid T1 mapping using multislice echo planar imaging

Abstract

Determination of neurological pathology in white matter disease can be made in a semiquantitative way from T1- or T2-weighted images. A higher level of quantification based on measured T1 or T2 values has been either limited to specific regions of interest or to low-resolution maps. Higher-resolution T1 maps have proved difficult to obtain due to the excessively long scan times required using conventional techniques. In this study, clinically acceptable images are obtained by using single-shot echo planar imaging (EPI) with an acquisition scheme that maximizes signal-to-noise while minimizing the scan time. © 2001 Wiley-Liss, Inc.