Abstract
PLINK is a versatile program which supports data management, quality control, and common statistical computations on matrices of genomic variant calls, in a computationally efficient manner. In population genomics, it is frequently used to take care of the “basics,” so they do not need to be reimplemented when a new type of analysis needs to be performed on such a matrix. I describe several of these basic operations, and discuss uses and pitfalls.
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Chang, C. C. (2020). Data management and summary statistics with PLINK. In Methods in Molecular Biology (Vol. 2090, pp. 49–65). Humana Press Inc. https://doi.org/10.1007/978-1-0716-0199-0_3
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