Abstract
Two new humulene-type sesquiterpenes, named hyptishumulene I (1) and II (2), have been isolated, together with eight known compounds, a humulene-type sesquiterpene (3), a monoterpene (4) and six abietane-type diterpenoids (5-10) from the aerial parts of Hyptis incana (Labiatae). The cytotoxic activity of the isolated compounds against mouse leukemia cells (L1210) was examined. The abietane-type diterpenoids (5-10) showed rather potent growth inhibitory activity (IC50<15 μM), while the new humulene-type compounds (1 and 2) exhibited moderate activity (IC50>50 μM).
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CITATION STYLE
Satoh, M., Satoh, Y., Anzai, Y., Ajisawa, D., Matsuzaki, K., Makino, M., & Fujimoto, Y. (2013). New humulenes from Hyptis incana (Labiatae). Natural Product Communications, 8(12), 1665–1668. https://doi.org/10.1177/1934578x1300801201
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