Xenopus laevis Oct-1 does not bind to certain histone H2B gene promoter octamer motifs for which a novel octamer-binding factor has high affinity

Abstract

Oct-1 and a second, previously unidentified octamerbinding protein (Oct-R) have been identified in extracts of Xenopus laevis oocytes and embryos. Oct-1 does not bind to the octamer motif associated with certain Xenopus laevis histone H2B gene promoters, whereas Oct-R binds well to this motif, but only in the sequence context of the H2B gene promoter. © 1991 Oxford University Press.