The preparation of (4: H)-imidazol-4-ones and their application in the total synthesis of natural products

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Abstract

(4H)-Imidazol-4-ones are an important scaffold for a variety of applications, including natural products, medicine, agriculture, and other applications. Over the years, there have been a number of preparations published for the synthesis of imidazol-4-ones. This review discusses the progress made on the synthesis of imidazol-4-ones, and their application towards the total synthesis of a range of imidazol-4-one containing natural products. Emphasis is made on areas of the field that still need progress.

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Keel, K. L., & Tepe, J. J. (2020). The preparation of (4: H)-imidazol-4-ones and their application in the total synthesis of natural products. Organic Chemistry Frontiers, 7(20), 3284–3311. https://doi.org/10.1039/d0qo00764a

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